What are the advantages of glass used in injection medicine in China?

In recent years, with the improvement of the level of science and technology and the rapid development of the pharmaceutical industry, many new products and technologies have emerged in the pharmaceutical packaging industry. How to make these achievements known and applied by pharmaceutical companies has become an important issue for the pharmaceutical packaging industry. To this end, this newspaper and China Pharmaceutical Packaging Association launched the "New Drug Packaging Stand" column, designed to introduce new packaging materials and packaging products, new processing technologies and processes, new production equipment and testing equipment, new or improved products Standards and test methods, etc., provide a platform for information disclosure and communication for drug packaging companies and pharmaceutical companies, and provide more support for the development of the pharmaceutical industry.

Drug packaging material has an important role in ensuring the quality of medicines and ensuring the safety of human medicine because of direct contact with medicines. As an integral part of pharmaceuticals, pharmaceutical packaging materials are closely related to the development of the pharmaceutical industry. The development priorities of the “Twelfth Five-Year Plan” pharmaceutical industry are: innovation and development to improve the scientific and technological level of the pharmaceutical industry and accelerate the development of pharmaceutical preparations. To adapt to it, stepping up the pace of technological innovation and constantly supporting the pharmaceutical industry with new products and technologies will become an important part of the development of the pharmaceutical packaging industry.

Neutral borosilicate glass has obvious advantages compared with the glass materials commonly used by domestic injection companies. First, it has a small expansion coefficient, is extremely cold and extremely hot, and is more suitable for freeze-dried products. Second, it is not easy to burst during processing. High mechanical strength, strong impact resistance; Third, chemical stability, high acid and alkali resistant water level, can guarantee the effective period of drugs, especially water needle preparations, reduce and avoid white spots, stripping and visible foreign body.

Medicinal glass is mainly used for the packaging of injections and other products, and its chemical stability directly affects the quality of drugs. Medicinal glass is classified into high borosilicate glass, neutral borosilicate glass, low borosilicate glass, and soda lime glass according to chemical composition and product performance. Neutral borosilicate glass has become an injection glass packaging material because of its excellent properties. New favorite."

Many countries in the United States, Japan, and Europe have long adopted neutral borosilicate glass in injections. Even countries such as Russia and India are actively promoting neutral borosilicate glass and eliminating low-borosilicate and soda-lime glass. In China, there are companies producing neutral borosilicate glass, but due to the high price and the need for pharmaceutical companies to change the packaging to make additional applications, the procedures are cumbersome, the time is long, and the enterprises involved are too much energy, so they are not widely used in production practice. application. However, relevant countries have begun to pay attention to it. The National Development and Reform Commission has included the first-class water-resistant medicinal glass for high-quality pharmaceutical packaging materials and technology development in the encouragement category in the “Guidance Catalogue for Industrial Structure Adjustment” in 2007; the China Pharmaceutical Packaging Association has also been committed to it. To promote the use of neutral borosilicate glass. It is believed that through the efforts of all parties, neutral borosilicate glass will be widely used.

The chemical stability of pharmaceutical glass refers to the ability of the glass to resist the erosive effects of gases or water, acids, alkalis, other chemical agents, and drug solutions. All along, China's injection packaging is based on low-borosilicate glass containers. The use of low borosilicate glass containers with a low water-tolerance level to fill the partially acidic and partial alkali liquids can easily lead to the appearance of dislodgment, white spots, and other foreign object detection items in the drug's validity period - especially those with pH , or water needle preparations, biological agents, vaccines, blood products that are sensitive to changes in pH.