U.S. develops a new machine to diagnose cancer with small samples

U.S. develops a new machine to diagnose cancer with small samples

Release date: 2009-04-22



In a groundbreaking development, American scientists have introduced a revolutionary cancer diagnostic tool that analyzes cancer-related proteins and tracks the effectiveness of treatments using only minimal samples—such as a single drop of blood or a tiny tissue sample. This innovation could potentially replace traditional surgical biopsies, which often require removing large tissue sections and administering anesthesia.

The new technology was developed by researchers at Stanford University. By analyzing the electrical charge of proteins associated with cancer, they can identify these proteins based on their surface characteristics. Antibodies are then used to detect the quantity and location of various proteins. This method has already shown promise in identifying the activity of cancer genes in common lymphoma samples and even differentiating between types of lymphoma. Dean Feels, a professor of oncology at Stanford who led the research, emphasized that the system can detect protein levels as low as picograms (10^-12 grams) and track subtle changes in protein behavior.

According to the researchers, the system offers a faster and more efficient way to monitor cancer treatment progress. While the initial focus was on blood cancers, the team is also exploring its potential for solid tumors, currently testing it on brain and neck tumors. They have successfully demonstrated the anti-cancer effects of a cholesterol-lowering drug in a lymphoma patient. Additionally, the technology has proven effective on lymphoma samples from laboratory mice and cultured tumor cells. This advancement could significantly improve early detection and personalized treatment strategies for cancer patients. Shanghai Medical Device Industry Association

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