The microwave drying and sterilizing process has obvious effects in the manufacture of oral liquid industry.

A large number of facts show that drying and sterilizing drugs with microwaves is much better than the traditional high-temperature drying sterilization process. This article illustrates the advantages of microwave sterilization equipment in pharmaceutical production lines by taking oral liquid, pills, capsules and tablets as examples.

It is well known that oral liquids contain sugar, biological agents and abundant nutrients, which are easily contaminated. Some oral liquids on the market, because they are not well sterilized, bacteria in the storage and reproduction, produce gas, users in the use of poisoning and bottle explosion accidents. Some oral liquid manufacturers, in order to prevent bacterial growth, add preservatives to the oral solution, the results can not go abroad. The microwave sterilization method can effectively solve the above problems, and the following is an analysis of the microwave sterilization method of the oral liquid microwave drying and sterilizing machine.

1, sterilization effect

The traditional method is to sterilize with high temperature steam, which needs to be warmed to 120 ° C, and the bacteria can be killed above 20 minutes. And microwave sterilization:

A. Escherichia coli and Bacillus subtilis can be completely killed in the microwave field by heating to 70 ° C for 2 minutes.

B. Thermophilic Bacillus subtilis, which needs to be warmed to 100 ° C by conventional methods, is kept for 30 minutes and cannot be killed. In the microwave field, the temperature was 70 ° C and kept for 2 minutes, which was killed. User feedback indicates that sterilization is performed with a 5 kW microwave device, killing bacteria in 50 seconds, and killing bacteria in an 8 kW microwave device for 35 seconds.

2. The degree of influence on the active ingredients of oral liquid

According to foreign literature reports, the use of microwave sterilization, the active ingredients of the drug will not decompose, sterilization by traditional methods, the decomposition of the active ingredients of the drug is obvious.

Compared with the traditional sterilization process, the microwave drying and sterilizing machine has low cost and small floor space, and the traditional high-temperature and high-pressure equipment needs to be equipped with a boiler pressure cooker, so that the cost is expensive and the floor space is large.

The microwave drying and sterilizing machine has low energy consumption, and the high temperature and high pressure equipment consumes a large amount of energy.

The microwave drying and sterilizing machine handles less staff, only 2 to 3 people, and the high temperature and high pressure equipment must be equipped with more than 10 staff for handling and treatment.

The microwave drying and sterilizing machine has low noise, while the high temperature and high pressure equipment has pollution and noise, which seriously affects the surrounding environment.

The microwave drying and sterilizing machine treats the oral liquid, which belongs to low temperature sterilization, can preserve the original nutrient, has clear brilliance and good taste; and the high temperature and high pressure treatment oral liquid destroys the original nutrient, turbid turbidity, precipitation, and poor mouthfeel.

In summary, the application of microwave in the oral liquid sterilization process is a challenge to the traditional medical process and a revolution in the pharmaceutical process. It is expected that all oral liquid manufacturers will adopt microwave oral administration in the near future. Liquid sterilization process.